Terms:
- Wild Type
- Sex-linked Gene
- Linked
- Genetic Recombination
- Parental Type
- Recombinant (Non-parental Type)
- Linkage Map
- Map Unit
- Barr Body
- Nondisjunction
- Aneuploidy
- Trisomy
- Monosomy
- Polyploidy
- Genomic Imprinting
Concepts:
- Know the kind of result you would expect from a cross involving two linked genes both when crossover occurs and when no crossover occurs.
- Be able to identify parental and recombinant gene combinations in dihybrid crosses involving linked genes.
- Know how the percentage of recombination can be used to determine map distances between genes. What effect do double crossovers have on the computed map distance?
- Know how sex is determined in humans and in selected other organisms like insects and birds.
- Know how sex-linked traits (genes) are inherited and how they would appear in a typical pedigree.
- Know about the common sex-linked traits in humans discussed in chapter 14, including something about their symptoms.
- Know the difference between sex-linked and sex influenced traits.
- Know about X-inactivation in females and its genetic significance.
- Understand the various problems that result from aneuploidy and polyploidy.
- Know the genetic causes and basic symptoms of Down syndrome, Patau syndrome, cri du chat syndrome, and the various aneuploid sex chromosome problems mentioned in class. See Table from class.
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